Yet 90 percent of current genetic studies occur in just 10 percent of the world’s population, which means the treatments being developed today may not work for the communities facing the largest burden tomorrow. Countries in the Global South have a genuine chance to leapfrog the fragmented, reactive healthcare systems developed nations built in the 20th century, integrating early detection into primary care and building clinical trial capacity from the ground up. Lower-cost, non-therapeutic prevention solutions being developed in the Global South can also help the Global North address its own Alzheimer’s burden: ultimately, treatments that work for everyone require data from everyone.
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